Référence mondiale incontestée en biologie cellulaire, cet ouvrage est divisé en 5 parties présentant : - les principes élémentaires et fondamentaux de la biologie cellulaire et de la biochimie ? ; - les mécanismes génétiques de base, les propriétés communes à la plupart des cellules eucaryotes, l'expression et la transmission des informations génétiques ; - les principales méthodes expérimentales d'étude des cellules, avec notamment, dans le chapitre 8, une nouvelle section intitulée "Analyse mathématique des fonctions des cellules" - l'organisation interne des cellules ; - le comportement des cellules dans les organismes multicellulaires, depuis les fonctions intercellulaires et la matrice extracellulaire, jusqu'aux réactions cellulaires liées à l'infection et au système immunitaire. Au cours de la préparation de cette nouvelle édition, ont été ajoutées de nouvelles sections, comme celles sur les nouvelles fonctions de l'ARN, les progrès de la biologie des cellules souches, les nouvelles méthodes pour étudier les protéines et les gènes et pour l'imagerie des cellules, les progrès de la génétique et du traitement du cancer, et le calendrier, le contrôle de la croissance et la morphogenèse dans le développement. Des résumés sont proposés en fin de chaque section, et à la fin des chapitres une rubrique intitulée "Ce que nous ne savons pas" offre un petit échantillon des questions et des défis sans réponse qui seront fondamentaux pour la prochaine génération de scientifiques. Une iconographie exceptionnelle de plus de 1500 illustrations permet de mieux aborder la complexité du sujet. Un important glossaire de plus de 1 400 définitions constitue un précieux outil pour le lecteur souhaitant contrôler ou compléter ses connaissances. L'ouvrage se termine par un index très détaillé de 12 000 entrées.

Biologie moléculaire de la cellule

Molecular Biology of the Cell

With a Foreword by John Oliver, host of Last Week TonightIn celebration of the 50th anniversary of its BBC debut, a revised and updated edition of the complete oral history of Monty Python-an insightful, in-depth portrait of the brilliant and hysterically funny show that transformed modern comedy. Broadcast by the BBC between 1969 and 1974, Monty Python's Flying Circus introduced something completely different: a new brand of surrealistic, stream-of-consciousness comedy that pushed the traditional boundaries of format, style, and content. Blending brilliant satire with slapstick silliness, The Pythons-Graham Chapman, John Cleese, Terry Gilliam, Eric Idle, Terry Jones and Michael Palin-spoke to a generation eager to break free of the conventional. Making their way across the Atlantic and the world, the Pythons' zany approach to comedy would have a monumental influence on modern popular culture, paving the way for farcical entertainment from Saturday Night Live to The Simpsons to Austin Powers. In Monty Python Speaks, David Morgan has collected interviews with Monty Python's founding members, actors, producers, and other collaborators to produce a no-holds-barred look at the Pythons' legendary sketches and films, including Monty Python's Life of Brian, Monty Python and the Holy Grail (the inspiration for the hit Broadway musical Spamalot), and The Meaning of Life. Featuring four new chapters that focus on the group's oeuvre since the first edition's publication twenty years ago, as well as a new foreword and updated resources, Monty Python Speaks offers a fascinating peek behind the scenes of the Pythons' creative process-including the friendships and feuds-that catapulted a comedy revolution.

Monty Python Speaks, Revised and Updated Edition - The Complete Oral History

A guide to side trips and excursions to the best Roman sites in Spain. Spain was an important part of the Roman Empire for almost 700 years. Evidence of Roman occupation can be found almost everywhere. This guide describes some of the most interesting archaeological sites from Roman and pre-Roman history, why they are important, and how you can visit them today. Learn about the Iberians, Phoenicians and Carthaginians, see where the great battles for control of the Iberian peninsula happened, admire Roman architecture and engineering, find Roman roads and temples, and enjoy modern Spanish food and culture along the way. An essential resource for anyone wanting to combine an interest in ancient history with a holiday in Spain.

Discovering Roman Spain

The complete oral history of Monty Python - one of comedy's most legendary and influential troupes - publishing to coincide with the 50th anniversary of their BBC debut.

 With a foreword by John Oliver from Last Week Tonight

 'Some people think it's very clever and intelligent, and some people say it's extremely silly and inconsequential, but not many people ignore it' Michael Palin

 With their dead parrots, holy grails and spam, Monty Python revolutionised comedy for the rest of the world. They paved the way for everything from Saturday Night Live to The Young Ones and The Simpsons, ushering in a new brand of surrealist comedy: a stream-of-consciousness sketch show that pushed the boundaries of format, style and content. Its legacy is not only important; it's monumental.

 In Monty Python Speaks!, David Morgan has extensively interviewed the entire world of Python - from producers and collaborators like Douglas Adams and Hank Azaria to the founding members themselves - to create the ultimate record of Britain's most rebellious and successful comedy act. Packed with rare and never-before-seen photographs, and told with the group's customary wit and irreverence, this newly updated edition, published to o is the inside story of a comedy phenomenon.

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