Fully revised and updated, this second edition of the second volume of the Atlases of electroencephalography series includes more than 2/3 new high-quality digital figures. A new Classification approach to epileptic seizures and to the epilepsies became official in 2017. Several aspects in terms of terminology have been included in this book and most of the chapters have been rewritten.

The second volume of this series on the practical use and interpretation of EEG focuses on epilepsies in their diversity. It is richly illustrated, and each EEG plate is analyzed in order to highlight the most significant elements to be used both for the diagnosis and interpretation. The originality of this textbook lies in its patient-based approach, thereby avoiding the pitfall of a formal presentation of EEG documents without their clinical context. Hence electroencephalography is placed at the core of the diagnostic and therapeutic discussion concerning patients with epilepsy.

Given the practical orientation of this Atlas, the focus is on common forms of epilepsies; nevertheless, some less common, more intriguing forms have also been illustrated. A synthetic text summarizes the present approach to the main epilepsy categories.

This Atlas is designed for all the actors who may be involved with patients with epilepsy. Physicians who deal with EEG will find it a valuable tool to improve the education of their early years, to help them with their interpretations later on, and for teaching purposes when more experienced. But it will also prove useful for all the physicians interested in epilepsy, as well as EEG technologists intent on providing quality recordings, and other professionals. Thorough understanding of human epilepsies requires extensive knowledge of their EEG correlates.

Atlas of Electroencephalography - Volume 2, The Epilepsies, EEG and Epileptic Syndromes

Since 1984, the year of the publication of its first edition, the famous "Blue Guide" has been the international reference for paediatricians and neuropaediatricians with regard to epileptic syndromes in infants, children and adolescents.

This 6th edition reviews some of the most noteworthy developments in the field, particularly in epileptic syndromes, but also focuses on the genetic aspects of the syndromes and their development. Progress brought about by advances in neuroimaging is also discussed in addition to specific etiologies such as parasitic diseases and immune and autoimmune diseases.

The different backgrounds of the contributors - coordinators and authors - ensure that the book's longstanding reputation for objectivity and seriousness, built over almost 35 years, remain well-deserved.

This book written by the current leading specialists is recognized worldwide as the international reference in epilepsy.

Epileptic Syndromes in Infancy, Childhood and Adolescence

Fully revised and updated, this second edition of the second volume of the Atlases of electroencephalography series includes more than 2/3 new high-quality digital figures. A new Classification approach to epileptic seizures and to the epilepsies became official in 2017. Several aspects in terms of terminology have been included in this book and most of the chapters have been rewritten. The second volume of this series on the practical use and interpretation of EEG focuses on epilepsies in their diversity. It is richly illustrated, and each EEG plate is analyzed in order to highlight the most significant elements to be used both for the diagnosis and interpretation. The originality of this textbook lies in its patient-based approach, thereby avoiding the pitfall of a formal presentation of EEG documents without their clinical context. Hence electroencephalography is placed at the core of the diagnostic and therapeutic discussion concerning patients with epilepsy. Given the practical orientation of this Atlas, the focus is on common forms of epilepsies ; nevertheless, some less common, more intriguing forms have also been illustrated. A synthetic text summarizes the present approach to the main epilepsy categories. This Atlas is designed for all the actors who may be involved with patients with epilepsy. Physicians who deal with EEG will find it a valuable tool to improve the education of their early years, to help them with their interpretations later on, and for teaching purposes when more experienced. But it will also prove useful for all the physicians interested in epilepsy, as well as EEG technologists intent on providing quality recordings, and other professionals. Thorough understanding of human epilepsies requires extensive knowledge of their EEG correlates.

More than half of epilepsies start before the age of 20 years and nearly 25% of them are refractory.  A tiny proportion of them are even labelled a "rare illness", i.e. one affecting less than 200,000 people in the United States or less than 5 out of 10,000 people in the European Union.  For these patients, two problems in their management arise:  In children, seizures affect an immature brain and can impact its development. It is therefore essential to treat them so that brain development continues as normally as possible. The rarity of these syndromes does not encourage the pharmaceutical industry to invest in research.   Therefore, there are few drugs available.  However, a few target syndromes with a particularly unfavourable diagnosis. This work outlines 6 molecules in detail that are specifically used in epileptic encephalopathies. Every aspect of these molecules is discussed, including drug development, indication, efficacy, cost, etc.  Drafted by international experts in the field of epileptology, it provides all the necessary information on orphan drugs and their clinical use.

Orphan Drugs in Epilepsy

More than half of epilepsies start before the age of 20 years and nearly 25% of them are refractory.

A tiny proportion of them are even labelled a "rare illness", i.e. one affecting less than 200, 000 people in the United States or less than 5 out of 10, 000 people in the European Union.

For these patients, two problems in their management arise:

- 

In children, seizures affect an immature brain and can impact its development. It is therefore essential to treat them so that brain development continues as normally as possible.

- 

The rarity of these syndromes does not encourage the pharmaceutical industry to invest in research.

Therefore, there are few drugs available.

However, a few target syndromes with a particularly unfavourable diagnosis. This work outlines 6 molecules in detail that are specifically used in epileptic encephalopathies. Every aspect of these molecules is discussed, including drug development, indication, efficacy, cost, etc.

Drafted by international experts in the field of epileptology, it provides all the necessary information on orphan drugs and their clinical use.

Le syndrome de Lennox-Gastaut est une des formes les plus sévères, mais aussi des plus " classiques ", des encéphalopathies épileptiques de l'enfant.
Son traitement reste difficile malgré l'apparition de nouvelles thérapeutiques anti-épileptiques, et l'accompagnement éducatif et social pose bien des problèmes à tous les stades et âges de cette pathologie. Dans un premier temps, les limites, critères et caractéristiques du syndrome de Lennox-Gastaut sont rappelés. Puis le point est fait sur les connaissances actuelles des bases physiopathologiques.
Enfin, à la lumière des récents progrès (disponibilité de nouvelles molécules, mise au point de stratégies thérapeutiques particulières et apparition de traitements non pharmacologiques), les conceptions thérapeutiques sont actualisées. Cette monographie s'inscrit dans une nouvelle série de mises au point synthétiques et abordables, à destination des cliniciens comme des chercheurs.

Le syndrome de Lennox-Gastaut

La 4ème édition de l'ouvrage les syndromes épileptiques de l'enfant et de l'adolescent est basée sur l'approche syndromique des épilepsies, marque distinctive de l'Ecole de Marseille et de l'épileptologie européenne. Faisant intervenir les plus grands spécialistes de l'épilepsie, cette 4ème version est totalement mise à jour et, point fort, enrichie cette année d'un CD-Rom des séquences vidéos des différents syndromes décrits dans l'ouvrage.

Les syndromes épileptiques de l'enfant et de l'adolescent

Jadis appelée " mal sacré " ou " haut mal ", l'épilepsie effraie encore. Elle est progressivement sortie du registre de la malédiction et de la possession, et, depuis la fin du XIXe siècle, des maladies psychiatriques, et reste une des maladies neurologiques les plus fréquentes, avec environ 400 000 personnes traitées actuellement en France. Les crises, les causes, les traitements sont très divers, et il est difficile de ne pas parler des épilepsies au pluriel. Les connaissances et les outils diagnostiques et thérapeutiques évoluent très vite dans le domaine des épilepsies humaines. Une vie normale, épanouie est cependant possible pour une grande majorité des patients. C'est ce qu'expliquent, à la lumière de leur expérience, les auteurs. Cet ouvrage s'adresse aux professionnels de santé, médecins et autres, qui désirent approfondir leurs connaissances sur les épilepsies, mais reste accessible à un public large : les patients et leur entourage y trouveront des réponses et des conseils.

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